4-methoxy-1H-indole-2-carboxylic acid
4-Methoxyindole-2-carboxylic acid
CAS: 103260-65-7
Molecular Formula: C10H9NO3
4-methoxy-1H-indole-2-carboxylic acid - Names and Identifiers
| Name | 4-Methoxyindole-2-carboxylic acid |
| Synonyms | AKOS JY2082663 IFLAB-BB F2137-0008 4-METHOXYINDOLE-2-CARBOXYLIC ACID 4-METHOXY-2-INDOLECARBOXYLIC ACID 4-Methoxyindole-2-carboxylic acid 4-Methoxy-1H-indol-2-carboxylic acid 4-METHOXY-1H-INDOLE-2-CARBOXYLIC ACID 4-Methoxy-1H-indole-2-carboxylic acid 4-methoxy-1H-indole-2-carboxylic acid 1H-Indole-2-carboxylic acid, 4-methoxy- |
| CAS | 103260-65-7 |
| EINECS | 607-884-2 |
| InChI | InChI=1/C10H9NO3/c1-14-9-4-2-3-7-6(9)5-8(11-7)10(12)13/h2-5,11H,1H3,(H,12,13) |
4-methoxy-1H-indole-2-carboxylic acid - Physico-chemical Properties
| Molecular Formula | C10H9NO3 |
| Molar Mass | 191.18 |
| Density | 1.381±0.06 g/cm3(Predicted) |
| Melting Point | 234-235 °C |
| Boling Point | 447.6±25.0 °C(Predicted) |
| Flash Point | 224.5°C |
| Vapor Presure | 8.54E-09mmHg at 25°C |
| pKa | 4.52±0.30(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Refractive Index | 1.677 |
4-methoxy-1H-indole-2-carboxylic acid - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| Hazard Class | IRRITANT |
4-methoxy-1H-indole-2-carboxylic acid - Introduction
4-methoxyindole-2-carboxylic acid is an organic compound whose chemical formula is C11H9NO3. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
4-methoxyindole-2-carboxylic acid is a light yellow solid with a special smell. It is soluble in organic solvents such as ethanol and dimethyl sulfoxide, but insoluble in water. The melting point of the compound is about 136-137°C.
Use:
4-methoxyindole-2-carboxylic acid has important applications in the fields of biochemistry and medicinal chemistry. It is an important chemical intermediate for the synthesis of a variety of bioactive molecules, such as pharmaceutical intermediates, plant growth regulators and pesticides.
Preparation Method:
4-methoxyindole-2-carboxylic acid can be prepared by methoxylation and carboxylation of indole. A common preparation method is to use indole as a raw material, first perform a methylation reaction, and then perform a carboxylation reaction on the basis of the methylated product. The specific preparation method can be selected and optimized according to actual needs.
Safety Information:
There is no specific risk report regarding the safety of 4-methoxyindole-2-carboxylic acid. However, as a chemical, it still needs to be stored and used properly. During use, care should be taken to avoid contact with skin and eyes, and to ensure that good ventilation conditions are provided. Any chemicals should be kept away from children and pets and avoid ingestion or misuse. If necessary, it is recommended to use under the guidance of professionals.
Nature:
4-methoxyindole-2-carboxylic acid is a light yellow solid with a special smell. It is soluble in organic solvents such as ethanol and dimethyl sulfoxide, but insoluble in water. The melting point of the compound is about 136-137°C.
Use:
4-methoxyindole-2-carboxylic acid has important applications in the fields of biochemistry and medicinal chemistry. It is an important chemical intermediate for the synthesis of a variety of bioactive molecules, such as pharmaceutical intermediates, plant growth regulators and pesticides.
Preparation Method:
4-methoxyindole-2-carboxylic acid can be prepared by methoxylation and carboxylation of indole. A common preparation method is to use indole as a raw material, first perform a methylation reaction, and then perform a carboxylation reaction on the basis of the methylated product. The specific preparation method can be selected and optimized according to actual needs.
Safety Information:
There is no specific risk report regarding the safety of 4-methoxyindole-2-carboxylic acid. However, as a chemical, it still needs to be stored and used properly. During use, care should be taken to avoid contact with skin and eyes, and to ensure that good ventilation conditions are provided. Any chemicals should be kept away from children and pets and avoid ingestion or misuse. If necessary, it is recommended to use under the guidance of professionals.
Last Update：2024-04-09 21:54:55
